A SHORT COMPILATION ON ZIKA VIRUS TRANSMISSION AND ITS COMPLICATION DURING PREGNANCY

Zika virus, a mosquito borne flavivirus transmitted primar­ily by Aedes aegypti mosquitoes is a pathogen affecting humans. These vectors also trans­mit dengue and chikungunya virus and are found throughout much of the world, including parts of the United States. An estimated 80% of persons infected with Zika virus are asymptomatic. Microcephaly is the greater risk for the infant born from the Zika Virus infected pregnant mother. This virus also causes neurological syndromes. Zika virus disease can often be diagnosed by performing reverse transcriptase-polymerase chain reaction (RT-PCR) on serum. Keywords: Zika Virus, Pregnancy, Microcephaly, Aedes aegypti mosquito, Brazil

Earthquake Impacts on the Livelihoods of Community Forest Users in Sindhupalchok District, Nepal, and Their Perceptions towards Forest Conservation

Community forests are a crucial component of farming systems and people’s livelihoods in the rural middle hills of Nepal, where the population depends upon the forest for fuelwood, fodder, and leaf litter for their daily needs. This study aims to assess the perception of community forest user groups towards their postearthquake situations by using the five forms of capital from the sustainable livelihood framework. It further analyzes whether forest user’s attitudes towards forest conservation have changed or not. In addition to household interviews with 68 earthquake-affected households and extensive visits to the study area, key informant interviews and focus group discussions were conducted. This study confirms that the community forest user groups perceived negative effects on the natural, physical, human, and financial capitals, whereas they perceived a positive effect on social capital after the earthquake. Controlled access to forest products, such as timber collection during the recovery phase, restricted their resilience, although nontimber forest products supported it. Low agricultural production because of the scarcity of water for irrigation, as well as the soil infertility because of the landslides, caused local people to shift towards nonagricultural activities for income generation. Further, out-migration for job opportunities resulted in an inflow of remittances and, thus, manpower shortages were observed. Our results show that, despite facing the postdisaster impact on their livelihoods, 92% of the respondents were found to be positive towards forest conservation. This was because of their emotional attachment to the forest and the benefits received from the forest in the past. Local institutional policies and mechanisms must be strengthened to provide communities with the knowledge, skills, and practices for effective postdisaster recovery or for upcoming disasters, as well as the benefits of promoting sustainable forest conservation

Earthquake Impacts on the Livelihoods of Community Forest Users in Sindhupalchok District, Nepal, and Their Perceptions towards Forest Conservation

Community forests are a crucial component of farming systems and people’s livelihoods in the rural middle hills of Nepal, where the population depends upon the forest for fuelwood, fodder, and leaf litter for their daily needs. This study aims to assess the perception of community forest user groups towards their postearthquake situations by using the five forms of capital from the sustainable livelihood framework. It further analyzes whether forest user’s attitudes towards forest conservation have changed or not. In addition to household interviews with 68 earthquake-affected households and extensive visits to the study area, key informant interviews and focus group discussions were conducted. This study confirms that the community forest user groups perceived negative effects on the natural, physical, human, and financial capitals, whereas they perceived a positive effect on social capital after the earthquake. Controlled access to forest products, such as timber collection during the recovery phase, restricted their resilience, although nontimber forest products supported it. Low agricultural production because of the scarcity of water for irrigation, as well as the soil infertility because of the landslides, caused local people to shift towards nonagricultural activities for income generation. Further, out-migration for job opportunities resulted in an inflow of remittances and, thus, manpower shortages were observed. Our results show that, despite facing the postdisaster impact on their livelihoods, 92% of the respondents were found to be positive towards forest conservation. This was because of their emotional attachment to the forest and the benefits received from the forest in the past. Local institutional policies and mechanisms must be strengthened to provide communities with the knowledge, skills, and practices for effective postdisaster recovery or for upcoming disasters, as well as the benefits of promoting sustainable forest conservation

Linkage of Depression with Elder Abuse among Institutionalized Older Persons in Kathmandu Valley, Nepal

Background. To identify the association between elderly abuse and depression among elderly living in old age homes of Kathmandu Valley, Nepal. Materials and Methods. A cross-sectional study was carried out in 5 old age homes of Kathmandu Valley, Nepal. The Geriatric Mistreatment Scale and the Geriatric Depression Scale were used to collect information from 220 elderly aged 65 or above, and face-to-face interviews were conducted. Bivariate and multivariate logistic regression analyses were carried out to identify the association between elderly abuse and geriatric depression. Results. Among the different types of abuse analyzed, the multivariate analysis showed that neglect (AOR=2.995; CI: 1.249-7.181) and economical abuse (AOR=4.728, CI: 1.836-12.173) were significantly associated with increased risk of geriatric depression. Furthermore, the study identified that future saving and absence of chronic disease significantly reduced the risk of psychological abuse, neglect, and geriatric depression. Conclusions. Neglect and economical abuse are a predictor of geriatric depression. Efforts should be directed to increase awareness about the different forms of abuse among the primary caregivers of the elderly. Counseling services and support programs should be introduced in old age homes to address the high burden of geriatric depression

Livestock and Poultry Production in Nepal and Current Status of Vaccine Development

The livestock and poultry sectors are an integral part of Nepalese economy and lifestyle. Livestock and poultry populations have continuously been increasing in the last decade in Nepal and are likely to follow that trend as the interests in this field is growing. Infectious diseases such as Foot and Mouth Disease (FMD), Peste des Petits Ruminants (PPR), hemorrhagic septicemia (HS), black quarter (BQ), swine fever, avian influenza, and Newcastle disease (ND) constitute one of the major health challenges to the Nepalese livestock and poultry industry. Vaccinations are an efficient means of preventing the occurrence and spread of several diseases in animals and birds. Considering this fact, the government of Nepal began the production of veterinary vaccines in the 1960s. Nepal is self-reliant in producing several vaccines for cattle and buffaloes, sheep and goats, pigs, and poultry. Despite these efforts, the demand for vaccines is not met, especially in the commercial poultry sector, as Nepal spends billions of rupees in vaccine imports each year. There is a need of strengthening laboratory facilities for the isolation and characterization of field strains of pathogens and capacity building for the production of different types of vaccines using the latest technologies to be self-reliant in veterinary vaccine production in the future in Nepal

Fatal pulmonary cavitary disease secondary to Mycobacterium xenopi in a patient with sarcoidosis

Introduction: Mycobacterium xenopi (M. xenopi) has low pathogenicity and usually requires either host immune impairment or structural lung disease to cause clinical disease. Fatal cavitary infection in a patient without immunosuppression is rarely presented. Case report: A 62-year-old female with history of sarcoidosis and hypertension presented with cough, fever and dyspnea for one week. Chest imaging showed irregular opacification of upper lung zones. The sputum samples tested positive for acid-fast bacilli (AFB) and the subsequent testing identified M. xenopi. She was started on rifampin, isoniazid, pyrazinamide and ethambutol along with azithromycin, and was discharged with plans to continue the same. A follow up sputum test was negative for AFB. She was, however, readmitted ten months later with sepsis due to pneumonia. Chest imaging revealed worsening cavitary lung lesions. Despite starting her on intravenous antibiotics while continuing anti-tubercular therapy, she developed severe respiratory distress and had to be intubated. Her condition continued to deteriorate and she expired the following day. Conclusion: Fatal cavitary infections with M. xenopi have been reported in the absence of established optimal management. Well-designed studies with sufficient power are needed to establish new treatment guidelines

Methods in the spatial deep learning: current status and future direction

A deep neural network (DNN), evolved from a traditional artificial neural network, has been seamlessly adapted for the spatial data domain over the years. Deep learning (DL) has been widely applied for a number of applications and a variety of thematic domains. This article reports on a systematic review of methods adapted in major DNN applications with remote sensing data published between 2010 and 2020 aiming to understand the major application area, a framework for model development and the prospect of DL application in spatial data analysis. It has been found that image fusion, change detection, scene classification, image segmentation, and feature detection are the most commonly used application areas. Based on the publication in these thematic areas, a generic framework has been devised to guide a model development using DL based on the methods followed in the past. Finally, recent trends and prospects in terms of data, method, and application of deep learning with remote sensing data are discussed. The review finds that while DL-based approaches have the potential to unfold hidden information, they face challenges in selecting the most appropriate data, methods, and model parameterizations which may hinder the performance. The increasing trend of application of DL in the spatial domain is expected to leverage its strength at its optimum to the research frontiers

Rare case of Mycobacterium nebraskense presenting as asymptomatic cavitary lung lesion

Introduction: Mycobacterium Nebraskense is a rare nontuberculous mycobacterial infection. The first isolate of the species was from human sputum at University of Nebraska Medical Center. There are only a few cases have been reported and the exact behavior of the disease is not clearly described. Here, we present a case from New York City incidentally found to have a cavitary lung lesion due to M. nebraskense. Case report: An 82-year-old female with a history of diabetes mellitus, hypertension, and dementia presented with constipation and urinary retention for 1 day. She had no fever, cough, shortness of breath, nausea, vomiting, appetite change, or weight loss. Computed tomography (CT) scan of abdomen and pelvis revealed retained fecal material in the colon, non-obstructing left renal calculus, and bilateral small pleural effusion with right-sided lung infiltrates. Subsequent CT scan of the chest showed 4.5 cm pleural-based opacity in right lung base with a small cavity. Sputum smear for Acid-fast bacilli was positive. Mycobacterial culture reported positive growth of M. nebraskense, while polymerase chain reaction returned negative for Mycobacterium gordonae, Mycobacterium kansasii, Mycobacterium avium complex and Mycobacterium tuberculosis. With the patient asymptomatic and her constipation improved, she was discharged with plans for close follow-up as outpatient. Conclusion: M. nebraskense is a very rare nontuberculous mycobacterial infection. From only a few cases reported in the USA, the exact presentation of infection, disease progression, and treatment have not been described well. Asymptomatic cavitary lung disease caused by M. nebraskense has not been reported before